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Original Contribution
JAMA. 1983;250(7):926-929. doi: 10.1001/jama.1983.03340070032022

Analysis of Narcotic Analgesic Usage in the Treatment of Postoperative Pain

  1. Kampon Sriwatanakul, MD;
  2. Otto F. Weis, FFA(SA);
  3. José L. Alloza, MD;
  4. William Kelvie;
  5. Michael Weintraub, MD;
  6. Louis Lasagna, MD
  1. From the Department of Pharmacology, University of Rochester School of Medicine and Dentistry, New York. Dr Alloza is a fellow of the Spanish Ministry of Health. Drs Sriwatanakul and Weis are Merck International Fellows.

Abstract

We reviewed 526 medical records of surgical patients and interviewed 81 of these patients. We also sent questionnaires to house staff (57 of 97 responded) and nurses (70 of 142 responded) involved in the care of these patients. A substantial number of patients suffered at least moderate pain during the postoperative period despite analgesic medication. Patients received 70% of the maximal ordered analgesic dose in the first 24 hours. Physicians prescribed drugs in doses that were often inadequate and to be given at inflexible intervals. The optimal doses and duration of action of meperidine, as judged by the house staff and nurses, did not agree with the accepted pharmacologic profile of this drug.

(JAMA 1983;250:926-929)

Footnotes

  • Reprint requests to Department of Pharmacology, University of Rochester Medical Center, Rochester, NY 14642 (Dr Lasagna).

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