Cigarette Smoking and Exposure to Passive Smoke Are Risk Factors for Cervical Cancer
- Martha L. Slattery, PhD, MPH;
- Linda M. Robison, MSPH;
- Katharina L. Schuman, PhD;
- Thomas K. French, M Stat;
- Thomas M. Abbott, MD;
- James C. Overall, Jr, MD;
- John W. Gardner, MD, DrPH
- From the Departments of Family and Preventive Medicine (Dr Slattery, Ms Robison, and Mr French), Pathology (Drs Abbott and Overall), and Pediatrics (Dr Overall), University of Utah School of Medicine, Salt Lake City; the Kaiser Permanente Center for Health Research, Portland, Ore (Dr Schuman); and the Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Md (Dr Gardner).
Abstract
Personal cigarette smoking and exposure to passive smoke as risk factors for cervical cancer were examined in a population-based, case-control study conducted in Utah. Personal cigarette smoking was found to increase the risk of cervical cancer, after adjusting for age, educational level, church attendance, and sexual activity. The adjusted risk estimate associated with being a current smoker was 3.42 (95% confidence interval [CI], 2.10 to 5.57); for having smoked for 5 or more pack-years, it was 2.81 (95% CI, 1.73 to 4.55); and for having smoked at least 100 lifetime cigarettes, it was 2.21 (95% CI, 1.44 to 3.39). The adjusted risk estimate (also adjusted for actual cigarettes smoked) associated with passive smoke exposure for 3 or more hours per day was 2.96 (95% CI, 1.25 to 7.03). Risk from passive smoking was greater in women who were not smokers (odds ratio, 3.43; 95% CI, 1.23 to 9.54) than in women who smoked (odds ratio, 2.59; 95% CI, 0.23 to 29.24).
(JAMA. 1989;261:1593-1598)
Footnotes
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Reprint requests to the Department of Family and Preventive Medicine, University of Utah School of Medicine, 50 N Medical Dr, Room 1C26, Salt Lake City, UT 84132 (Dr Slattery).
