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JAMA. 1991;265(23):3135-3137. doi: 10.1001/jama.1991.03460230085023

Nephrology

  1. Shaul G. Massry, MD
  1. University of Southern California School of Medicine, Los Angeles

Since this article does not have an abstract, we have provided the first 150 words of the full text.

Excerpt

Research directed at further understanding the factors that contribute to the progression of renal failure dominates the field of nephrology.1 Major advances have occurred, and it has become well accepted that hypertension in patients with renal insufficiency of any origin is a major risk factor. Strict control of hypertension can delay or prevent the progression of renal insufficiency to endstage renal failure.

The role of dietary protein restriction in preventing the progression of renal failure has not yet been established. Although the results of many investigations support a beneficial effect of protein restriction, its wide-scale application should await definite documentation. The National Institute of Diabetes and Digestive and Kidney Diseases is currently sponsoring a multicenter controlled study of the effects of several dietary protein regimens on the progression of renal failure in patients with varying degrees of renal insufficiency. The study will be completed in 2 years, and the

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