Reduction of Bacteriuria and Pyuria Using Cranberry Juice
- Louis M. Katz, MD
Since this article does not have an abstract, we have provided the first 150 words of the full text.
Excerpt
To the Editor. —While it is attractive in these high-tech times to embrace low-tech approaches to disease prevention and control, Dr Avorn and colleagues1 have not made their case for cranberry juice. From data in Table 1 of the article (page 753), it is apparent that their randomization and/or blinding scheme failed and that the two groups were not comparable with regard to previous UTI (Table). Analysis of the history of UTI for the prior 6-month and 12-month periods demonstrates a significant excess in the placebo group during both periods (P=.004, odds ratio [OR]=4.39, 95% confidence interval 1.55 to 12.43, using the approximation of Woolf, and P=.03, OR=2.50, 95% confidence interval 1.15 to 5.42, using the approximation of Woolf, respectively [Fisher's exact test]), suggesting the placebo group was more likely at baseline to experience UTI or bacteriuria/pyuria than the treatment group.
