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Landmark Perspective
JAMA. 1996;276(22):1796-1798. doi: 10.1001/jama.1996.03540220020011

The Heritage of Hepatitis B Vaccine

  1. R. Gordon Douglas, Jr, MD
  1. From the Merck Vaccine Division, Merck & Co Inc, Whitehouse Station, NJ.

Abstract

Pioneering development of the plasma-derived and yeast-derived recombinant hepatitis B vaccines represents a major contribution to preventive health care of this century. Current and expanding worldwide application of hepatitis B vaccine promises to eliminate and eventually eradicate hepatitis B infection from the human population and, with it, many cases of cirrhosis and cancer of the liver.

Footnotes

  • Reprints: R. Gordon Douglas, Jr, MD, Merck Vaccine Division, Merck & Co Inc, One Merck Dr, PO Box 100, Whitehouse Station, NJ 08889-0100.

  • A commentary on Buynak EB, Roehm RR, Tyteli AA, Bertiand AU II, Lampson GP, Hilleman MR. Vaccine against human hepatitis B. JAMA. 1976;235:2832-2834.

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