Bisphenol A and Risk of Metabolic Disorders
- Frederick S. vom Saal, PhD;
- John Peterson Myers, PhD
- Author Affiliations: Division of Biological Sciences, University of Missouri, Columbia (Dr vom Saal); Environmental Health Sciences, Charlottesville, Virginia (Dr Myers).
Since this article does not have an abstract, we have provided the first 150 words of the full text.
- KEYWORDS:
- BISPHENOL A
- ESTRADIOL
- ESTROGENS
- HAZARDOUS SUBSTANCES
- METABOLIC DISEASES
- PUBLIC HEALTH
- UNITED STATES FOOD AND DRUG ADMINISTRATION
Published online September 16, 2008 (doi:10.1001/jama.300.11.1353).
In this issue of JAMA, Lang and colleagues1 report the results of the first major epidemiologic study to examine the health effects associated with the ubiquitous estrogenic chemical bisphenol A (BPA). This compound is the base chemical (monomer) used to make polycarbonate plastic food and beverage containers, the resin lining of cans, and dental sealants; it also is found in “carbonless” paper used for receipts as well as a wide range of other common household products. Based on their analysis of data from the National Health and Nutrition Examination Survey 2003-2004, Lang et al report a significant relationship between urine concentrations of BPA and cardiovascular disease, type 2 diabetes, and liver-enzyme abnormalities in a representative sample of the adult US population. This report, suggesting links between BPA and some of the most significant and economically burdensome human diseases, is based on a …
