JAMA Multimedia Index Page

Open and Endovascular Repair of Abdominal Aortic Aneurysm

Animated Figure for Schermerhorn M. JAMA. 2009;302(18):2015-2022.

This animation explains local anatomy and key steps in both open and endovascular repair of an abdominal aortic aneurysm.

Rotating 3-dimensional Fluorodeoxyglucose F18-Positron Emission Tomography Whole-Body Maximal Intensity Projection Image

Supplement to Masciari S, Van den Abbeele AD, Diller LR, et al. F18-Fluorodeoxyglucose–Positron Emission Tomography/Computed Tomography Screening in Li-Fraumeni Syndrome. JAMA. 2008;299(11):1315-1319.

This animated figure supplement displays a rotating whole-body maximal intensity projection image of an individual with Li-Fraumeni Syndrome and gastroesophageal junction cancer.

Overview of Reverse Cholesterol Transport and High Density Lipoprotein Metabolism

Supplement to Singh IM, Shishehbor MH, Ansell BJ. High-Density Lipoprotein as a Therapeutic Target: A Systematic Review. JAMA. 2007;298(7):786-798.

This animated figure supplement provides an overview of how high-density lipoprotein may protect against cardiovascular disease through the mechanism of reverse cholesterol transport.

Computed Tomographic Angiogram of Abdominal Aortic Aneurysm

Interactive figure for for Schermerhorn M. JAMA. 2009;302(18):2015-2022.

This interactive figure displays computed tomographic angiogram images that demonstrate the presence of an abdominal aortic aneurysm from the patient case, Mr F.

Transport Service Areas for US Burn Centers

Interactive figure for Klein MB, Kramer CB, Nelson J, et al. JAMA. 2009;302(16):1774-1781.

These interactive maps display the locations of verified and self-reported US burn centers and the geographic regions within 1, 2, and 4 hours by ground transport and 1 and 2 hours by rotary air transport.

Distribution of Cerebrospinal Fluid Aβ42:P-Tau Ratio and T-Tau Levels in Healthy Controls, Patients With Alzheimer Disease, and Patients With Mild Cognitive Impairment

Interactive figure for Mattsson N, Zetterberg H, Hansson O, et al. CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment. JAMA. 2009;302(4):385-393.

The 3 panels of this interactive figure show the distribution of cerebrospinal fluid (CSF) Aβ42:P-Tau Ratio and T-Tau Levels in healthy controls, patients with Alzheimer disease, and patients with mild cognitive impairment relative to an 85% sensitivity cutoff for diagnosis of incipient Alzheimer disease among patients with mild cognitive impairment.

Co-occurrence of Chromosomal Alterations and Tumor-Promoting Gene Interactions in Gliomas

Interactive figures for Bredel M, Scholtens DM, Harsh GR, et al. A Network Model of a Cooperative Genetic Landscape in Brain Tumors. JAMA. 2009;302(3):261-275.

Interactive figure 1 displays chromosomal maps showing (A) the associations between chromosomal territories that displayed co-occurrence of gene dosage alterations in gliomas in discovery and validation sets (validated genetic landscape) and (B) the network of highly connected genes with cooperatively tumorigenic relationships in the validated genetic landscape.

Interactive figure 2 displays the complete network model of 214 cooperatively tumorigenic glioma genes and their functionality and alterations in expression.

Distribution of Oseltamivir-Resistant Influenza A(H1N1) Viruses Identified in the United States, 2007-2008

Supplement to Dharan NJ. Infections With Oseltamivir-Resistant Influenza A(H1N1) Virus in the United States. JAMA. 2009;301(10):1034-1041.

This interactive map displays the number of oseltamivir-resistant influenza A(H1N1) viruses identified in each state.

Normal Upper Extremity and Chest Anatomy and Examples of Targeted Muscle Reinnervation

Supplement to Kuiken T, et al. Targeted Muscle Reinnervation for Real-time Myoelectric Control of Multifunction Artificial Arms. JAMA. 2009;301(6):619-628.

This interactive figure displays the normal muscular anatomy and innervation of the major muscles of the chest, shoulder, back, and arm, and examples of targeted muscle reinnervation surgery for patients with shoulder-disarticulation and transhumeral amputation.

Targeted Muscle Reinnervation for Advanced Prosthetic Arms

Supplement to Kuiken T, et al. Targeted Muscle Reinnervation for Real-time Myoelectric Control of Multifunction Artificial Arms. JAMA. 2009;301(6):619-628.

This multimedia feature explains how targeted muscle reinnervation (TMR) is used to control advanced prosthetic arms. Three patients who underwent TMR surgery demonstrate this technology.

Computed Tomography Angiography for Detection of Peripheral Arterial Disease

Supplement to Met R. Diagnostic Performance of Computed Tomography Angiography in Peripheral Arterial Disease. JAMA. 2009;301(4):415-424.

This interactive figure displays the anatomy underlying a computed tomography angiogram in an individual with peripheral arterial disease. The image demonstrates total occlusion of the left common iliac artery with severe calcification.

Abdominal Ultrasound of a Woman with Uterine Fibroids

Supplement to Van Voorhis B. A 41-Year-Old Woman with Menorrhagia, Anemia, and Fibroids. JAMA. 2009;301(1):82-93.

This interactive figure displays the anatomy underlying an abdominal ultrasound of a woman with uterine fibroids. The large fibroids distort the shape of the uterus.

MRI of Individual With Mild Cognitive Impairment

Supplement to Ellison JM. A 60-Year-Old Woman With Mild Memory Impairment. JAMA. 2008;300(13):1566-1574.

This interactive figure displays the anatomy underlying a T2-weighted fluid attenuated inversion recovery magnetic resonance image in a case patient with mild cognitive impairment. The image demonstrates bilateral subcortical and periventricular discrete and confluent T2-enhancing white matter lesions with no significant cortical atrophy.

Serial Magnetic Resonance Imaging of a Brainstem Hemagioblastoma Demonstrating Peritumoral Cyst Formation in a Patient with von Hippel-Lindau Disease

Supplement to Butman JA, Lineham WM, and Lonser RR. Neurologic Manifestations of von Hippel-Lindau Disease. JAMA. 2008;300(11):1334-1342.

This interactive figure displays the anatomy underlying serial MRIs of a brainstem hemangioblastoma that demonstrate formation of a peritumoral cyst in a patient with von Hippel-Lindau disease.

Interactive Anatomical Model of the Normal L4-5 Functional Spinal Unit and Associated Neural Structures

Supplement to Rathmell JP. A 50-Year-Old Man With Chronic Low Back Pain. JAMA. 2008;299(17):2066-2077.

This interactive model of the normal functional spinal unit displays the anatomical relationships between the L4 and L5 vertebrae and the cauda equina and associated spinal nerves.

Model of Influenza B Neuraminidase Monomer

Supplement to Hatakeyama S, Sugaya N, Ito M. Emergence of Influenza B Viruses With Reduced Sensitivity to Neuraminidase Inhibitors. JAMA. 2007;297:1435-1442.

This interactive supplement is a rotatable model of an influenza B neuraminidase monomer that demonstrates the location of mutations associated with reduced sensitivity to neuraminidase inhibitors.

3D Model of Basal Ganglia

Supplement to Voelker R. Scientists Use Neuroimaging, Genetic Studies to Probe Biology of Tourette Syndrome. JAMA. 2004;292:909-911.

This interactive supplement is a rotatable 3-dimensional computer model of the caudate, putamen, and globus pallidus, in which surface structures were extracted automatically from magnetic resonance imaging data.

Ligamentous and Meniscal Injuries of the Knee: Basic Anatomy and Functional Examination

Supplement to Solomon DH, Simel DL, Bates DW, Katz JN, Schaffer JL. Does This Patient Have a Torn Meniscus or Ligament of the Knee? JAMA. 2001;286:1610-1620.

This interactive module illustrates knee anatomy and demonstrates maneuvers used to perform a thorough functional examination of the knee.

Simulation of Floaters

Video for Hollands H, Johnson D, Brox AC, et al. JAMA. 2009;302(20):2243-2249.

This video simulates the appearance of floaters as experienced by an individual scanning an open landscape.

Tubular Diskectomy vs Conventional Diskectomy for Treatment of Sciatica

Supplement to Arts MP, Brand R, van den Akker ME, et al. Tubular Diskectomy vs Conventional Microdiskectomy for Sciatica: A Randomized Controlled Trial. JAMA. 2009;302(2):149-158.

These videos demonstrate representative cases of the 2 surgical techniques compared in this randomized trial among patients with sciatica due to lumbar disk herniation.

Intramyocardial Bone Marrow Cell Injection in a Patient With Chronic Myocardial Ischemia

Supplement to van Ramshorst J, Bax JJ, Beeres SLMA, et al. Intramyocardial Bone Marrow Injection for Chronic Myocardial Ischemia. JAMA. 2009;301(19):1997-2004.

This video explains how intramyocardial bone marrow cell injection is performed and shows a patient with chronic myocardial ischemia undergoing this procedure.

Nasal Endoscopy

A 51-Year-Old Woman With Acute Onset of Facial Pressure, Rhinorrhea, and Tooth Pain. JAMA. 2009;301(17):1798-1807.

Video of a normal nasal endoscopy.

A 74-Year-Old Man With Memory Loss and Neuropathy Who Enjoys Alcoholic Beverages

Video supplement to Brust, J. A 74-Year-Old Man With Memory Loss and Neuropathy Who Enjoys Alcoholic Beverages. JAMA. 2008;299(9):1046-1054.

In this video supplement, Mr E describes the loss of strength and function he has experienced in his hands and demonstrates atrophy of the intrinsic muscles of his hands and claw deformities of his fourth and fifth fingers. The video also shows the examination of Mr E's gait.

Use of Indigo Carmine Solution in Endoscopic Identification and Resection of Nonpolypoid Colorectal Neoplasms

Video supplement to Soetikno RM, Kaltenbach T, Rouse RV et al. Prevalence of Nonpolypoid (Flat and Depressed) Colorectal Neoplasms in Asymptomatic and Symptomatic Adults. JAMA. 2008;299(9):1027-1035.

This video supplement demonstrates the use of indigo carmine solution to identify a flat, nonpolypoid adenoma followed by endoscopic mucosal resection of the lesion.

Transthoracic Echocardiogram of a Patient With Sickle Cell Disease and Pulmonary Hypertension

Video supplement to Barnett CF, Hsue PY, and Machado RF. Pulmonary Hypertension: An Increasingly Recognized Complication of Hereditary Hemolytic Anemias and HIV Infection. JAMA. 2008;299(3):324-331.

This video supplement includes the 2-dimensional and color doppler echocardiograms of the case patient with sickle cell disease and pulmonary hypertension presented in the companion JAMA article.

Pulmonary Vein Radiofrequency Catheter Ablation Therapy for Atrial Fibrillation

Video supplement to Marine JE. Catheter Ablation Therapy for Supraventricular Arrhythmias. JAMA. 2007;298(23):2768-2778.

This video provides an overview of the technique of circumferential pulmonary vein catheter ablation for the treatment of atrial fibrillation. This example demonstrates the integration of a patient's pre-acquired computed tomography or magnetic resonance cardiac images with a 3-dimensional electroanatomical mapping system during the procedure to guide the ablation, including catheter manipulation and identification of ablation sites.

Echocardiogram of a Patient With Cardiac Tamponade

Supplement to Roy CL, Minor MA, Brookhart MA, Choudhry NK. Does This Patient With a Pericardial Effusion Have Cardiac Tamponade? JAMA. 2007;297:1810-1818.

In this video supplement, a large circumferential pericardial effusion compressing the heart is visualized by transthoracic echocardiography in a patient with cardiac tamponade.

Detection of Patent Foramen Ovale Using Contrast Transesophageal Echocardiography

Supplement to Allemann Y, Hutter D, Ernst L, et al. Patent Foramen Ovale and High-Altitude Pulmonary Edema. JAMA. 2006;296:2954-2958.

This video supplement demonstrates the detection of a patent foramen ovale using contrast transesophageal echocardiography in the long axis view.

3D Imaging of Head and Neck Vasculature

Supplement to Zeller JL. New 3D Imaging Software Opens New Vistas. JAMA. 2006;296:2908-2913.

This supplement shows a video capture of 3D imaging of the vasculature of the head and neck created from noncontrast magnetic resonance imaging data.

Doppler Auscultation of the Posterior Tibial Artery

Supplement to Khan NA, Rahim SA, Anand SS, Simel DL, Panju A. Does the Clinical Examination Predict Lower Extremity Peripheral Arterial Disease? JAMA. 2006;295:536-546.

This audiovisual supplement displays the anatomy, technique, and sound characteristics of Doppler auscultation of the posterior tibial artery of a healthy individual.

Intravascular Ultrasound to Measure Progression of Atherosclerosis

Supplement to Nissen SE, Tuzcu EM, Schoenhagen P. Effect of Intensive Compared With Moderate Lipid-Lowering Therapy on Progression of Coronary Atherosclerosis. JAMA. 2004;291:1071-1080.

This video supplement demonstrates the technique of intravascular ultrasound imaging and determination of atheroma area before and after lipid-lowering therapy.

Use of Augmented Reality for Laparoscopic Adrenalectomy

Supplement to Marescaux J. Augmented-Reality–Assisted Laparoscopic Adrenalectomy. JAMA. 2004;292:2214-2215.

This video demonstrates the preoperative and intraoperative use of augmented reality for laparoscopic adrenalectomy in a patient with Conn adenoma.

Mitochondrial Movement in a Cortical Neuron

Supplement to Friedrich MJ. Scientists Probe Roles of Mitochondria in Neurological Disease and Injury. JAMA. 2004;291:679-681.

This time-lapse movie shows mitochondria moving along the cytoskeleton of a single cortical neuron transfected with mitochondrially targeted yellow fluorescent protein.